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Unique opportunity to evaluate genetic contribution to auditory processing skills. Five tests of auditory processing were administered to twins attending the 2002 and 2003 Annual Twins Festival in Twinsburg, Ohio. This was conducted as a pilot study to gain experience administering a central auditory processing research protocol outside of a controlled clinical setting. The five tests administered were the Filtered Words FW ; , Auditory FigureGround AFG ; and Competing Words CW ; subtests of theSCAN-A Keith 1995 ; , a dichotic consonant vowel CV ; test, and the Click Order Lateralization Test COLT ; developed by F. Musiek. Testing was conducted in a trailer. Sound attenuating earmuffs in combination with insert earphones were used to reduce ambient noise. Normal pure-tone hearing sensitivity for 500-4000 Hz and normal tympanometry were confirmed for each participant prior to administration of the auditory processing tests. By comparing scores between monozygotic MZ ; and dizygotic DZ ; twin pairs, an estimate of the heritability of auditory processing skills was made. The CW subtest of the SCAN-A gave the strongest evidence for heritablily. MZ concordance was 0.8 while DZ concordance was ~ 0.55. These rates are not significantly different, mostly due to the small sample size for the DZ group 54 MZ pairs; 11 DZ pairs; p 0.099 ; . At the present time we estimate the fraction of the variability on CW test performance that can be attributed to hereditary factors h2 ; to be approximately 57%. The other tests of auditory processing skills showed little differences in concordence rates between MZ and DZ twins and thus provided no evidence for significant contribution of hereditary factors in test performance levels.
Fig. 4. Effect of carbaryl A ; and thiabendazole B ; on DNA repair in two human lymphoblastoid cell lines, i.e. the parental line cHol and its CYP1A1 stably transfected counterpart, h1A1v2. Cells were treated with DMSO 0.5% ; , carbaryl or thiabendazole 100 and 250 M ; for 72 hr with a change of chemical-containing medium every 24 hr. DNA damage was monitored by unscheduled DNA synthesis DNA ; 3D assay. The data are expressed as means SD from three determinations, for instance, sleeping pill.
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The FY 2000 Strategy was based on a comprehensive Needs Assessment conducted by OCJS and has as its priorities: promoting the philosophy of community-oriented policing COP ; , reducing violent crime, making available effective treatment correctional programming for adjudicated convicted offenders, promoting the collection and use of justice-related data, promoting restoration of crime victims, sustaining and expanding coordination of multi-jurisdictional enforcement agencies, and promoting equity and efficiency in the administration of criminal justice. To meet these priorities OCJS offered eight program areas in which local constituents could apply during CY 2003. Multi-Jurisdictional Law Enforcement Task Forces This program was one of the top priorities indicated in the 2000 Needs Assessment. This program contributes to the goal of controlling illegal drugs by identifying, investigating, and arresting drug traffickers operating multi-jurisdictional areas. 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By intervening in the drug-crime calendar year, this program contributes to both the goals of controlling illegal drugs and reducing violent crime. Non-Compensation Assistance for Jurors, Witnesses and Victim Services Findings from the 2000 Byrne Needs Assessment were supplemented by OCJS's 2001 Family Violence Needs Assessment. There is notable variation in needs and resources throughout the state, especially the great need and limited resources in the Appalachian counties. Effective victim's services contribute to the long-term overall operations of the justice system. Effective intervention can also contribute to a reduction in violent crime. Treatment Programs for Drug and Alcohol Dependent Offenders One of the greatest needs discovered in the 2000 Needs Assessment was treatment services for offenders. This is especially true for mentally ill offenders and substance abusing offenders. 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