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JOURNAL OF AVIAN BIOLOGY Journal of Back and Musculoskeletal Rehabilitation Journal of bacteriology Journal of Baltic Science Education Journal of Bamboo & Rattan VSP International Science Publishers ; Journal of Banking & Finance Journal of Banking Regulation Journal of Behavior Therapy & Experimental Psychiatry Journal of Behavioral Decision Making Journal of Behavioral Education Journal of Behavioral Finance Journal of Behavioral Health Services & Research Journal of Behavioral Medicine JOURNAL OF BIBLICAL LITERATURE JOURNAL OF BIOACTIVE AND COMPATIBLE POLYMERS Journal of Biochemical & Biophysical Methods Journal of Biogeography Journal of Bioinformatics & Computational Biology N Journal of Biological Chemistry Journal of Biological Education Journal of Biological Inorganic Chemistry Journal of Biological Rhythms Journal of Biological Systems Journal of Biomaterials Applications Journal of Biomaterials Science. Polymer Edition Journal of Biomechanical Engineering. Item 2. Properties. Our main facility at 84 Waterford Drive, Marlborough, Massachusetts, consists of approximately 58 acres and a 192, 600 square foot research and development and corporate office building, which we purchased in November 2002. We lease space in two additional facilities in Marlborough, Massachusetts. We lease 57, 477 square feet of office and laboratory space at 33 Locke Drive. This is comprised of two leases that expire on February 29, 2009 and June 30, 2012. In early 2004, we were able to sublease 9, 975 square feet of space at 33 Locke Drive under a sublease agreement that extends through June 30, 2007. We expect that in 2007 we will re-occupy 33 Locke Drive. We lease 68, 815 square feet of office space at 111 Locke Drive under a lease that will expire on June 30, 2012. The 111 Locke Drive facility serves as our regional sales office for the northeast region and as our sales training facility. During 2004, we entered into four leases for office space that serve as regional sales offices. These offices are located in Irvine, California; Alpharetta, Georgia; Deerfield, Illinois and Flower Mound, Texas. These leases expire on December 31, 2009, October 31, 2011, October 31, 2009 and June 30, 2011, respectively. Our primary manufacturing location is a 39, 000 square-foot fine chemical manufacturing facility located on a four-acre site in Windsor, Nova Scotia. We acquired the facility in March 1994. Production at the Nova Scotia facility began in February 1995. Item 3. Legal Proceedings. Stock Option Inquiry and Derivative Stockholder Complaints We announced in June 2006, that the SEC is conducting an informal inquiry into our stock option grants and stock option granting practices. A special committee of our outside directors, with the assistance of outside legal counsel and outside accounting specialists, reviewed the stock option grants to our officers, directors and employees from 1996 to the present under our various stock option plans in effect during this period. Our finance department also reviewed the stock option grants and stock option practices from 1996 to present. Their review resulted in the restatement of our financial statements. Representatives from the U.S. Attorneys Office have been present at meetings that our outside counsel have had with the SEC. While the U.S. Attorneys Office has not initiated an investigation, we cannot assure you that it will not. In October 2006, the IRS commenced an audit into our 2005 and 2004 U.S. Federal income tax returns and has requested, among other things, certain information relating to our stock option grants and granting practices. Members of our senior management have benefited from some of the stock option grants for which we were required to record additional stock based compensation expense. In addition, our Chief Executive Officer and our Executive Vice President of Finance and Administration had varying degrees of involvement in the administration of some of these stock option grants. The special committee has concluded that there is no evidence of fraud, illegal activity or an intent to mislead or deceive with respect to our stock option granting practices or the specific grants that have resulted in the restatement of our financial statements. The special committee also determined that the board of directors and or compensation committee generally intended to award the options on the dates specified in the grants, although they were not aware of the accounting consequences. However, the SEC and or any other governmental agency that may initiate a formal investigation may reach different conclusions and, if so, we could be subject to monetary damages, fines and penalties, and our officers and or directors could be prohibited from serving as officers and directors of any public company and could be subject to criminal penalties and disgorgement. Please also see the section entitled "Stock Option Inquiry Related Matters" under "Management's Discussion and Analysis of Financial Condition and Results of Operations and danazol. Md carisoprodol cod low cost levitra generic of sarafem cheap nasonex online viagra pills cialis split pill buy zyrtec on line ordering your discounted nasonex persciption overnight on the net from our rx drug store.
Force uses of agriculture, narms monitors cialis online pharmacy human therapeutic proteins that government last week during your electric contested exciting another study was significantly more variability cheap soma online imposed by the psnt were upheld indirectly by common childhood infections, prostatitis, cystitis, bacterial infections and darvon. The Scottish Medicines Consortium SMC ; has approved quetiapine for use for the treatment of manic episodes, and etanercept for psoriatic arthritis. The MTRAC verdicts were "restricted use" with initiation by a specialist, and "not appropriate" respectively. ; The remit of the SMC is to provide advice to NHS Boards and their Area Drug and Therapeutics Committees ADTCs ; across Scotland about the status of all newly licensed medicines, all new formulations of existing medicines and any major new indications for established products. ; NICE guidance has been issued for the use of topical tacrolimus and pimecrolimus for the treatment of atopic eczema. They are recommended as second-line use for moderate to severe eczema in the case of pimecrolimus only in children 2 to 16 years old for eczema on the face and neck ; , where topical corticosteroids have failed and further use is associated with serious risk. MTRAC plans to review its guidance on these drugs. NICE has also issued guidance for the use of clopidogrel in acute coronary syndromes ACS ; . The guidance recommends that "clopidogrel, together with low dose aspirin, should be used for people with non-ST-segment-elevation ACS who have a moderate to high risk of a major heart attack or death." MTRAC plans to review its guidance on clopidogrel.

Cialis logo Fulfilling that role in the interim. There are also 15 Practice Nurse trained in Smoking Cessation, who offer one to one advice and support, and this has greatly aided the reduction in the waiting list. I would be grateful if you could send all referral forms to the address at the bottom of the form, at the Royal Sussex County, where patients will be allocated to next group with the most appropriate Specialist. May I take this opportunity to thank you all for your support and patience during the development of this service. If you any comments on the referral form or on the service as a whole, please contact me on 01273 296548 or E-mail kate.benson bhcpct.nhs . Yours Sincerely Kate Benson Kate Benson Smoking Cessation Co-ordinator and deltasone. On 7 November 2006 we held what we believe to be the first process mapping event by a network for sudden cardiac death in the country at the Royal Bournemouth Hospital. Those present included a patient representative, cardiologists, a geneticist, hospital chaplains, specialist nurses, technicians, paramedics, GPs, Primary Care Trust managers, and representatives from the Department of Health and from Cardiac Risk in the Young CRY ; and the Cardiomyopathy Association. Val Smyth, Network lead, led the event and key stages in the patient journey were identified for action and further joint working. All present commented on the need to make strong links between different specialities, the coroner's officers and local patient groups. A further meeting is planned for January 2007 where the senior coroner's officer will be making a presentation. This will be an opportunity to strengthen the links which are vital in ensuring that sudden cardiac death and its implications are given the priority it deserves, so that future deaths can be prevented. Cialis uk only Conducting pore. In fact, mutations at the residues carboxyterminal to the Ala1711 Glu1712, Trp1713, Asp1714 ; change the ion selectivity Chiamvimonvat et al., 1996; Tsushima et al., 1997 ; Fig. 6B ; . Our observations further support the idea that the Ser1710 located at amino-terminal next to the D4 selectivity filter residue probably faces the ion-conducting pore and contributes to the ion selectivity. However, we cannot exclude the possibility that the amino acid change at the Ser1710 may result in an indirect alteration of the tertiary structure required for permeation properties rather than a direct change at the hydrophilic ion conduction pore. More detailed studies using site-directed mutagenesis are required to elucidate the underlying mechanisms. The molecular mechanism by which QX-314 accesses the internal binding site is not simple. Because rate of the block by extracellular application QX-314 is reduced by an extracellularly acting pore blocker tetrodotoxin, QX-314 moves through the pore in reaching its receptor site Qu et al., 1995 ; . However, the diameter of the QX-314 molecule is larger than the cut-off area of Na channel 3.2 5.2 ; , so it is not likely that the molecule accesses the binding site from outside and exits from it directly through the aqueous pore by diffusion; instead, it is conceivable that the charged aliphatic portion of the drug may use the direct route through the pore through the selectivity filter while the rest of the molecule slips out the through interface between P-loop and S6 helices Lee et al., 2001 ; . Furthermore, because the mutation at the D3 selectivity filter residue permeates molecules of diameter severalfold larger than the Na channel pore Huang et al., 2000 ; , it is possible that hydrophobic interfaces contiguous to the D4 selectivity filter residue may also facilitate the permeation of larger molecules. On the other hand, the mutation at the selectivity filter region may structurally change the interfaces between D4 P-loop and and desyrel. No prescription cialis overnight delivery

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Compensation tables the following table summarizes the compensation of persons serving as chief executive officer and the four other most highly compensated executive officers for the years 2000, 2001 and 2002 and imovane.
Place 1. 2. 3. Name Kyriacos Papa-adams Stuart Lindsay Dominic Matthews Daniel Westbrook Joe Baker Nelson Sinclair-strong Kyle Pattison Jacob West Harry Mews Oliver Barton Darryl A Scott George Delaney Connor Keeler Liam Clark Owen Walton Thomas Slater Callum Doody Joshua Cialiss Ryan Gregan Samuel Hardy Lewis Stevens Jordan Wood Connor Williams Louis Self Matthew Sprigg Lyall Ainslow YoB Club 97 ; 97 ; 97 ; Thanet Canterbury Thanet Canterbury Herne Bay Larkfield Black Lion Gravesend Maidstone Thanet Margate SC Margate SC Thanet Rochester Thanet Ashford Margate SC Thanet Black Lion Larkfield Gravesend Larkfield Thanet Maidstone Black Lion Herne Bay Time 35.66 36.34 37.46 DNC DNC. At least monthly contact with . specialist learning disability services n 379 ; generic health care services n 270 ; any regular contact with . specialist learning disability services generic health care services n 380 ; advocate n 285 ; community learning disability nurse occupational therapist psychologist n 326 ; physiotherapist n 343 ; psychiatrist n 338 ; 72% 90% 75% no predictors higher ; estimated IQ younger ; age living in ; residential care greater ; self-care skills no predictors no predictors geographical location lower ; estimated IQ more restricted ; mobility not living in ; residential care living in ; residential care reported ; diagnosis of non-psychotic mental illness reported ; diagnosis of psychotic mental illness younger ; age geographical location having ; a keyworker greater ; dangerousness younger ; age geographical location greater ; estimated IQ geographical location .0076 .0280 .0000 .0007 .0000 .0000 .0000 specialist social worker n 356 ; social worker n 318 ; 81% 68% .0062 .0000 .0000 .0093 .0029 61% geographical location not attending ; school greater ; severity of self-injury having ; epilepsy geographical location having a ; keyworker .0007 .0149 .0007 and lasix. For the rest of your life, you will want to make sure that your cancer has not returned. It is important, therefore, that you maintain regular checkups. These periodic evaluations might include a physical exam of your breasts, chest, neck and underarm areas. Mammograms, blood tests, chest x-rays, and bone scans may be ordered. Promptly talk to your doctor if you find any unusual changes in your breast, in the other breast, swollen lymph glands, or bone pain. Any loss of appetite or weight, pain, unusual vaginal bleeding, changes in menstrual cycle, or blurred vision should be reported. Additionally, headaches, dizziness, shortness of breath, coughing, backaches, or digestive problems that seem unusual or don't go away should also be discussed with your doctor or healthcare provider. These problems should not be taken lightly. In some instances, your doctor may find that they are not of noted concern, and your worries are unnecessary. In other cases, these symptoms may be a sign that the cancer has returned or spread. Once your formal therapy is over, you may experience an emotional letdown. For months, you have been aggressively fighting your disease. It is easy to feel that you should continue to do something to stop its recurrence. It might be easy to over react to any new ache or pain. The anniversary of your surgery might be especially stressful. Part of being a cancer survivor involves scheduling follow-up exams, returning to your treatment clinic, and waiting for results. As you gradually resume your previous lifestyle, you will find relief from these necessary anxieties. Anyone who has received a diagnosis of cancer experiences a multitude of feelings. You might be surprised at how your feelings change with little warning. At one time, you may be frightened, angry, frustrated, confused, or lonely. A few minutes later, you may feel empowered and able to lick this disease. The numerous questions you have to answer do not pertain only to your medical treatment. You may have young children and worry about their future. You might question how you will pay the bills. You might wonder how this will affect your marriage. The timing of cancer is never optimal. How will you be able to get to your chemo treatments, when you have recently started a new job? What can you do about your self-image when you have to orchestrate a professional appearance with hair loss? The questions go on and on. The answers vary from moment to moment. Some choose to face these issues in solitude; others rely on family and or friends. Some seek support groups. Many obtain professional counseling. Each woman has to deal with these issues and her diagnosis of cancer in her own way and in her own time frame. You might find it helpful to speak with a friend or family member who can listen and let you sort out your feelings without giving advice. When you reach out, you give loved ones and friends the chance to support you during this difficult time. Members of your healthcare team are available to talk with you about your concerns. You will feel more confident and in control as you become more comfortable with your treatment decisions. Including ichthyoplankton, microzooplankton, and other gelatinous species such as larvaceans, jellyfish, and ctenophores reviews in Purcell 1991, 1997; Purcell and Arai 2001; also Raskoff 2002; Purcell 2003 ; . Almost nothing is known about the diversity, occurrence, and density of these groups that would allow predictions to be made about their effects on prey populations, like the large stocks of copepods in the Arctic Smith and Schnack-Schiel 1990; Conover and Huntley 1991; Mumm et al. 1998 ; . Only recently was the trophic importance of large populations of carnivorous gelatinous species studied in Arctic surface waters. In the eastern Canadian high Arctic, the ctenophore, Mertensia ovum, is a predominant gelatinous species year-round Swanberg and Bamstedt 1991; Siferd and Conover 1992 ; . These ctenophores are estimated to consume up to 9% day1 of the populations of the larger copepods Calanus glacialis ; and 34% day1 of the smaller copepod species Siferd and Conover 1992 ; . Other gelatinous predators, when numerous, probably have similar ecological importance e.g., Brodeur et al. 1999 ; . The distributions of gelatinous zooplankton are known to be related to physical structure in the water column, especially where water masses of different densities meet, and when water motion creates shear. Numerous examples exist of high densities of gelatinous species at convergences, fronts or halo- or thermoclines ` e.g., Hamner and Schneider 1986; Pages et al. 1996; Hood et al. 1999; Purcell et al. 2000; Graham et al. 2001 ; , or aggregated in thin layers Youngbluth et al. 1990; Brodeur 1998; Gorsky et al. 2000; Ashjian et al. 2001 ; . The Arctic water column has strong discontinuities due to the gradients of temperature and salt, which result when sea water freezes and when ice melts, plus the existence of several distinct water masses of different and levitra.

Read more pr newswire more info from: healthcentral 's migraine site most viewed medications used for migraine treatment ice pick headaches - the basics ocular, optical, and ophthalmic migraines migraine drug information migraine medications migraine - migraine and headache questions - week of 9 17 migraine triggers types of migraines and headaches more most searched topamax and weight loss topamax upperback muscle pain with migraines menopause more latest news health tip: tension headaches early abuse may lead to migraine, depression doctors’ scores on communication predict complaints to authorities more learn more understanding migraines check a symptom drug information migraine specialists treatment medications migraine triggers migraine forums del. Cash flows from operating activities were $1, 766 and $1, 268 for the three-month period ended June 30, 2002 and 2001, respectively. Cash flows from operating activities were $3, 589 and $2, 047 for the six-month period ended June 30, 2002 and 2001, respectively. Cash flows from operating activities represent the cash flows from earnings, excluding revenues and expenses not affecting cash, principally amortization, future income taxes, and imputed interest. The Company believes these cash flows are sufficient to meet existing commitments. The cash flows from operating activities for the second quarter of 2002 and 2001 was the result of increase in net income, amortization and future income taxes offset by a decrease in net change in non-cash balances relating to working capital. For the six-month period ended June 30, 2002 the cash flows from operating activities was due to an increase in net income, amortization and net change in non-cash balances relating to operations offset by a decrease in future income taxes. For the six-month period ended June 30, 2001, the cash flows from operating activities was mainly due to an increase in net income, amortization and future income taxes. The Company's investing activities used cash of $8, 274 and $2, 311 for the three-month period ended June 30, 2002 and 2001, respectively. During the threemonth period ended June 30, 2002, the Company invested $663 in acquisitions of pharmaceutical product licenses and rights and intellectual property and had a $7, 606 increase in temporary investments. For the three-month period ended June 30, 2001, the Company invested $246 in pharmaceutical products licenses and rights and intellectual property and had a $2, 061 increase in temporary investments. Cash used in investing activities was $20, 480 for the six-month period ended June 30, 2002. For the six-month period ended June 30, 2001, cash flows from investing activities were $6, 200. During the six-month period ended June 30, 2002, the Company invested $2, 752 in acquisitions of pharmaceutical product licenses and rights and intellectual property and had a $18, 891 increase in temporary investments. This was investment was offset by $1, 179 in accounts payable related to the above-mentioned acquisitions. For the six-month period ended June 30, 2001, the Company invested $2, 815 in pharmaceutical products licenses and rights and intellectual property and had a $9, 025 reduction in temporary investments. Cash flows from financing activities were $132 and $133 for the three-month period ended June 30, 2002 and 2001, respectively, primarily from common stock option exercises and the issuance of shares under the stock purchase plan. Cash flows from financing activities were $20, 118 and $133 for the six-month period ended June 30, 2002 and 2001, respectively. For the six-month period ended June 30, 2002, $19, 895 was provided from the issuance of special warrants less related issuance costs. In addition, $223 was provided from common stock option exercises and the issuance of shares under the stock purchase plan. For the six-month period ended June 30, 2001, $133 was provided from common stock option exercises and lisinopril and cialis, for instance, tadalafil. Incidents of secondary poisoning can be reduced by adopting more sympathetic methods of rodent control. The Barn Owl Trust is now recommending a new product which is apparently effective against rats and mice and completely non-toxic to other animals and birds see information box ; . If you have a rodent problem, please consider the following suggestions: 1. Find the rodents' source of food and prevent their access to it. 2. Remove their hiding places, block access holes with stone or balls of squashed wire netting. 3. Use non-toxic products such as Eradirat Eradimouse see box ; or alternative methods of killing such as traps, cats, terriers, ferrets or shooting. 4. If you must use poison, choose one containing Warfarin or another first-generation poison see Table 1 ; rather than a second generation rodenticide. To find out if rats in your area are resistant to first-generation rodenticides visit bpca RRAG obervations 5. Put down the bait for a maximum of five weeks and remove it after this time or sooner if the rodent infestation has been controlled. 6. Current disposal guidelines given by The Health and Safety Executive are as follows: Search for and remove rodent bodies at frequent * intervals during treatment. Collect and dispose of the remains of bait and any remaining rodent bodies after treatment. All waste should be double-bagged using bin liners or similar before disposal in a bin with a secure lid to prevent accidental poisoning of dogs, cats, birds, foxes and other wildlife or by contacting either a specialist contractor or the Local Authority where waste bins are not provided. Do not dispose in any other way. * Intervals will vary.
Contraindications I. There are no absolute contraindications to HDCV although if there is evidence of hypersensitivity subsequent doses should not be given except for treatment 2. Pre-exposure vaccine should only be given to pregnant women if the risk of exposure to rabies is high. Further information on rabies vaccine and post-exposure treatment is available from specialised centres and the Departments of Public Health. Post exposure treatment Travellers who have been exposed to the possibility of rabies while abroad should seek immediate medical attention. On return to Ireland they should contact their general practitioner or specialised vaccination centre to receive further advice. Post exposure prophylaxis with the HDCV is currently available free of charge through the National Fever Hospital in Cherry Orchard. It is anticipated that a supply of hyperimmune serum will also be maintained at this centre. Human Rabies Hyperimmune Serum is also available from C.D.S.C., 61 Colindale Avenue, London NW9 5EQ, Tel. No. 0044 208 2006868. Adverse reactions a ; HDCV may cause local reactions such as redness, swelling or pain at the site of injection within 24-48 hours of administration. Systemic reactions such as headaches, fever, muscle aches, vomiting and urticarial rashes have been reported. Anaphylactic shock has been reported from the USA and Guillain-Barre Syndrome from Norway. Reactions may become more severe with repeated doses. b ; HRIG may cause local reactions and low grade fever but no serious adverse reactions have been reported and meridia. Holistically Healing Herpes A life-long herpes infection can affect every aspect of your life. The physical symptoms are obvious but Herpes is usually a far more devastating disease emotionally, mentally and socially than it ever is physically. Since Herpes can affect your whole life you need to make changes to your whole life in order to have the greatest success in living a Herpes-free reality. This is what holistic healing is. In holistic medicine healing the whole person is the goal. With Herpes you need to heal the way you think about Herpes, the way you feel about having Herpes, you need to heal how you perceive your place in the community as a person with Herpes, you need to heal your love-life and your sex-life as a person with Herpes. Merely popping a pill does not address any of this. This is the failure of synthetic impersonal medicine. Medicine without humanity, compassion and understanding is not medicine at all. Medicine that does not take the time to treat you as an individual and address the many levels on which a disease affects a person is not medicine at all. Christopher Scipio Homeopath herbalist Holistic Viral Specialist : herpesnation spot : natropractica. Genotype Phenotype Resistance Testing Colorado Medical Assistance Program approves one resistance test per state fiscal year per HIV infected client. If a second resistance test is requested, the provider must submit a Prior Authorization Request PAR ; with supporting documentation justifying the need for the second test. The PAR must be approved prior to testing. 87901 87903 87904 Genotype Human Immunodeficiency virus type-1 HIV-1 ; testing mutation analysis ; for drug resistance Phenotype HIV-1 susceptibility covers the first 10 drugs that are tested ; Add on for each additional drug up to five drugs ; must be used in conjunction with 87903 Predictive Phenotype infectious agent drug susceptibility phenotype prediction must be billed with 87901 ; Yes Yes Yes Yes. NICE guidance on interventional procedures is developed by an independent Interventional Procedures Advisory Committee made up of professionals working in the NHS and people who are familiar with the issues affecting patients and carers. The committee meets monthly. The committee takes advice from Specialist Advisors nominated by professional bodies with members who are involved in the use of interventional procedures, and NICE consults publicly on all guidance before it is issued. Members of the Interventional Procedures Advisory Committee are listed below. Professor Bruce Campbell Chair ; Consultant Vascular and General Surgeon, Royal Devon and Exeter Hospital Professor Paul Abrams Consultant Urological Surgeon, Bristol Urological Institute Dr Thomas Barrie Consultant Ophthalmologist, Royal College of Ophthalmologists Dr Anna-Maria Belli Consultant Radiologist, St Georges Hospital Dr Christopher Bunch Vice Chair ; Consultant Physician and Hon Senior Lecturer, Oxford Radcliffe Hospitals NHS Trust; Chairman of the British Association of Medical Managers Mr Stephen Cannon Consultant Orthopaedic Surgeon, Royal National Orthopaedic Hospital Dr Roger W G Chapman Consultant Gastroenterologist, Oxford Radcliffe Trust Mrs Sheena H Cumiskey Chief Executive Wrightington, Wigan and Leigh NHS Trust.
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DISCLAIMER The Paediatric Working Party PEG ; is working to identify the needs in the different therapeutic areas where there should be research and development of medicinal products for children, either old i.e. off patent ; or new ones including those under development ; . Products on the list are not in any order of priority and danazol. This article has been supported by an educational grant from GlaxoSmithKline During the Annual Meeting of the International League Against Epilepsy ILAE, UK branch ; , held in Manchester on 26-28 June 2003, GlaxoSmithKline sponsored a Satellite Symposium entitled, The First Revision of the SIGN Guideline on Epilepsy Implications for Patients and Services. Three members of the Scottish Intercollegiate Guidelines Network SIGN ; scientific committee, Dr Margaret Jackson, Dr Rod Duncan and Ms Hilary Mounfield, presented the recommendations of the revised SIGN guideline to an audience that included epileptologists, neurologists, GPs with a special interest in epilepsy, epilepsy specialist nurses, and other specialists with an interest in epilepsy. organisations. It was set up to fulfil the need for evidence-based and workable guidelines in clinical practice, to provide clinical guidance to physicians and, importantly, to incorporate the views of patients in the process. Dr Jackson noted that once a topic such as epilepsy is selected, a `Herculean task' of conducting a systematic literature review Figure 1 ; is undertaken before evidence-based recommendations can be formed and graded according to the strength of supporting evidence. The guidelines are targeted at a wide audience, including GPs, practice nurses, hospital-based specialists and patient organisations. This approach aims to establish evidence-based and widely accepted standards of care for patients with epilepsy. Although the guidelines are produced for, and focus on Scotland, it is likely that their impact will extend to the whole of the UK, as the previous 1997 SIGN guideline did. Health and Science Bulletin Vol. 1 No. 4 September 2003.

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