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Methods for reporting medication errors include anonymous self-reports, incident reports, critical incident techniques, and direct observation. Incident reports are often used to report medication errors in the hospital setting, however this method of reporting requires an awareness of the error and staff participation may be low due to fear of disciplinary action. Without an understanding of the safety of the medication process within the pharmacy department, it is difficult to know if a specific incident report is reflective of the medication process or simply an isolated event. The purpose of this study is to create a method to identify and quantify errors associated with pharmacist medication order review, then use the method to conduct an assessment of the medication order review process, and finally to make recommendations for ongoing use of the method within the department. The study is a retrospective, disguised-observation design. All medication orders written for patients on a general medical unit were collected from a ten-day period in January. Each written medication order was compared to the order input into the pharmacy computer system and evaluated for correctness. The components of the medication order that were evaluated included patient name, drug name, dose, route, frequency, time, start stop date, instructions for use, renal dose adjustments, duplicate therapy, significant drug interactions, and allergy information. It is expected that 2500 medication orders will be reviewed. The results will be used to calculate a departmental error rate. Sub-group analyses will be used to identify trends and determine if the discrepancies can be associated with centralized services, technician order entry, weekend shifts, or specific times of day. Recommendations will be made for routine implementation of the review process. Data analysis is currently in progress and the conclusions will be presented at the Great Lakes Conference. Learning Objectives: Summarize the various medication error reporting methods used in the hospital setting. Perform an error rate calculation. Self Assessment Questions: An advantage of the disguised-observation study design is that it is independent of a subject's willingness to report a medication error. [T F] Medication order entry discrepancies were associated with centralized pharmacy services. [T F]. Table mean standard deviation ; post-ecs step-through latencies s ; in rats that received ecs or sham ecs and nitroprusside or saline n 10 per cell ; main effects for drug, p 00 main effect for ecs, p 00 drug × ecs interaction, nsecs, electroconvulsive shock, for example, tobradex. 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Late of a methicillin-sensitive S aureus with a predetermined MIC50 inhibits 50% of strains ; of 0.5 g mL for ciprofloxacin. The other 2 experiments were performed in an identical fashion by inoculating either S pneumoniae or P aeruginosa. Twelve hours after the injection, the rabbits were randomized to 4 treatment groups, with 6 rabbits in each group: 1 ; ciprofloxacin, 3 mg mL Ciloxan 0.3%; Alcon Laboratories, Fort Worth, Tex 2 ; ofloxacin, 3 mg mL Ocflox 0.3%; Allergan, Irvine, Calif 3 ; trovafloxacin mesylate, 5 mg mL TrovanIV; Pfizer, New York, NY and 4 ; preservative-free 0.9% nonbacteriostatic isotonic sodium chloride solution for intravenous use control ; . Trovafloxacin eyedrops were prepared using the intravenous solution that was transferred into a dropper bottle under a sterile hood. The eyedrops were administered every hour for 12 hours. One hour after the last dose of eyedrops, the rabbits were systemically anesthetized and then humanely killed by intracardiac injection of pentobarbital sodium Beuthanasia-D Special; Schering-Plough Animal Health Corp, Kenilworth, NJ ; . The rabbits' corneas were excised using a sterile, disposable, 7.5-mm corneal trephine and irrigated with 3 mL of phosphatebuffered saline to eliminate any residual antibiotic or debris on the surface of the corneas. The corneal buttons were immediately homogenized and then serially diluted before plating in duplicate on blood agar for S aureus and S pneumoniae and on Mueller-Hinton II agar for P aeruginosa. The specimens were incubated at 35C for 24 hours before quantitative bacteriologic analysis. RESULTS. Ocuflox sale
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