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SynthroidEven though I have not found the benefits to be great, I sometimes persuaded to treat when weight loss or fatigue is the patient's concern, and they also have a slightly abnormal TSH level. Other times, when the decision to treat a slightly abnormal TSH levels is not straight-forward, I may suggest a six month trial on thyroid and look for subjective feelings of well-being ; and objective lower cholesterol ; improvements. Thyroid supplementation is one of the very few treatments I commonly prescribe. See my November 2004 newsletter for a more complete list of McDougall-used medications. ; For my patients with a damaged thyroid gland, correcting hypothyroidism with the right amount of levothyroxine can be an inexpensive medical miracle without side effects. References: 1a: Spencer CA. Demers LM. LMPG: Laboratory Support for the Diagnosis and Monitoring of Thyroid Disease Published Guidelines ; : : nacb lmpg thyroid 3c thyroid.doc 1 ; Dong BJ, Hauck WW, Gambertoglio JG, Gee L, White JR, Bubp JL, Greenspan FS. Bioequivalence of generic and brand-name levothyroxine products in the treatment of hypothyroidism. JAMA. 1997 Apr 16; 277 15 ; : 1205-13. 2 ; Crapo LM. Subclinical hypothyroidism and cardiovascular disease. Arch Intern Med. 2005 Nov 28; 165 21 ; : 2451-2. 3 ; Roberts CG, Ladenson PW. Hypothyroidism. Lancet. 2004 Mar 6; 363 9411 ; : 793-803. 4 ; Ayala AR, Wartofsky L.The case for more aggressive screening and treatment of mild thyroid failure. Cleve Clin J Med. 2002 Apr; 69 4 ; : 313-20. 5 ; Imaizumi M, Akahoshi M, Ichimaru S, Nakashima E, Hida A, Soda M, Usa T, Ashizawa K, Yokoyama N, Maeda R, Nagataki S, Eguchi K. Risk for ischemic heart disease and all-cause mortality in subclinical hypothyroidism. J Clin Endocrinol Metab. 2004 Jul; 89 7 ; : 3365-70. 6 ; Monzani F, Caraccio N, Kozakowa M, Dardano A, Vittone F, Virdis A, Taddei S, Palombo C, Ferrannini E. Effect of levothyroxine replacement on lipid profile and intima-media thickness in subclinical hypothyroidism: a doubleblind, placebo- controlled study. J Clin Endocrinol Metab. 2004 May; 89 5 ; : 2099-106. 7 ; Rodondi N, Newman AB, Vittinghoff E, de Rekeneire N, Satterfield S, Harris TB, Bauer DC. Subclinical hypothyroidism and the risk of heart failure, other cardiovascular events, and death. Arch Intern Med. 2005 Nov 28; 165 21 ; : 2460-6. 8 ; Use Armour thyroid rather than Synthroid: : mercola 1999 archive armour thyroid 9 ; Bunevicius R, Kazanavicius G, Zalinkevicius R, Prange AJ Jr. Effects of thyroxine as compared with thyroxine plus triiodothyronine in patients with hypothyroidism. N Engl J Med. 1999 Feb 11; 340 6 ; : 424-9. 10 ; Escobar-Morreale HF, Botella-Carretero JI, Gomez-Bueno M, Galan JM, Barrios V, Sancho J. Thyroid hormone replacement therapy in primary hypothyroidism: a randomized trial comparing L-thyroxine plus liothyronine with L-thyroxine alone. Ann Intern Med. 2005 Mar 15; 142 6 ; : 412-24. Merck sponsored ; . 11 ; Siegmund W, Spieker K, Weike AI, Giessmann T, Modess C, Dabers T, Kirsch G, Sanger E, Engel G, Hamm AO, Nauck M, Meng W. Replacement therapy with levothyroxine plus triiodothyronine bioavailable molar ratio 14 : 1 ; not superior to thyroxine alone to improve well-being and cognitive performance in hypothyroidism. Clin Endocrinol Oxf ; . 2004 Jun; 60 6 ; : 750-7. No sponsor listed ; 12 ; Clyde PW, Harari AE, Getka EJ, Shakir KM. Combined levothyroxine plus liothyronine compared with levothyroxine alone in primary hypothyroidism: a randomized controlled trial. JAMA. 2003 Dec 10; 290 22 ; : 2952-8. Sponsor, National Naval Medical Center ; see page 6.
She found no difference between the expensive brand, synthroid and the inexpensive generic, levothroid.
As many as 15% of people taking nonsteroidal antiinflammatory drugs have a temporary increase in liver blood tests while taking the medication.
To one brand of thyroid hormone and not another? Mr. Gascoigne responded: "Thank-you for the question. This is actually a very popular question: Which is better Sunthroid or Eltroxin? They are both very good sources of levothyroxine manufactured by reputable companies. They are also both made under strict quality control guidelines. One brand is not "better" than another. however they are not exactly the same. A Synthgoid 0.1mg tablet contains: 100ug levothyroxine sodium, acacia, confectioner's sugar, D&C Yellow No.10, FD&C Yellow No.6, lactose, magnesium stearate, povidone and talc. An Eltroxin 0.1mg tablet contains: 100ug levothyroxine sodium, acacia, Colorcon yellow, cornstarch, lactose and magnesium stearate. Although the active ingredient i.e. levothyroxine ; is exactly the same in each of the brands, the non-medicinal or "filler" ingredients are slightly different. In theory, this can result in very small differences in absorption of levothyroxine. For the vast majority of patients taking thyroid medication this usually presents no difficulties. However, a patient being treated for thyroid cancer needs to keep his her TSH very tightly controlled so a small change for these individuals may make a noticeable difference and the TSH level should be tested if the brand is changed. I have no doubt about who cleaned up in 1998. There may have been a few speed bumps on Wall Street, but for America's trial attorneys, it has been another banner year. Lawsuits are now more notable for the fees plaintiffs' lawyers collect than for the actual recovery their clients receive. Consider a recent class action settlement in a case filed against several New York brokerage firms. The plaintiffs' lawyers were just awarded $144 million in fees -- four times more than what they would have received had they been billing at their hourly rates. Take the antitrust class action involving the thyroid drug Synthroid. The proposed settlement called for $28 million in attorney fees, while the recovery for the individual clients averaged $19.60 per person. The contingency-fee bar in Texas and Florida expects a $5 billion payday for filing tobacco lawsuits that never even Daniel J. Popeo Chairman went to trial. Washington In a prison inmate's suit against the state of Ohio, the trial court granted a fee request of $50, 523 for his attorney. Legal Foundation The client received $235 in damages. In still other cases, lawyers get millions of dollars while their clients simply get to apply for discount coupons from the defendants they just sued. Regrettably, situations like these have become all too common. These are case studies in greed. Should lawyers get all the cash while their clients get the leftovers? As America's legal industry squeezes every drop of profit it can out of our judicial system, our laws are being stretched to the outer limits. Where is all of this litigation lotto money going? It's being used to finance even more lucrative litigation. Much of the money will also go to bankroll the campaign coffers of friendly judges who will make the system even more accommodating to plaintiffs' lawyers and their dubious, but rewarding, legal theories. We currently have the specter of profit-driven lawyers Our laws are being determining which industry will make their hit list. Who will the enterprising trial lawyers go after next? Stand by for stretched to the lawsuits from cardiac patients alleging negligent Big Mac outer limits. attacks and caffeine overdoses. We now have tyranny by litigation. The plaintiffs' attorneys seek to portray themselves as noble public servants helping the victims of evil corporate America. They argue that their entrepreneurial lawsuits serve the common good even though they can cripple entire industries. Who elected the trial lawyers to decide who will lose their jobs? For all of you Dow Jones enthusiasts out there, it's fair to ask: what will this continued costly litigation mean for America's sustained economic growth? As consumers, we have to pick up the tab for the trial lawyers' huge judgments. We pay hidden litigation taxes in everything we buy. Isn't it about time we all got a litigation tax cut? and tobradex.
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Protected formulation contains many constituents such as green tea, phosphatidyl cholina along with turmeric. Obviously turmeric has not been patented as such but seems to play a significant role in various formulations. Another patent entitled "Anti Inflammatory herbal composition and method of use" was granted in May 2002 by the USPTO to Thomas Newmark and Paul Schulick. The invention relates to a composition having turmeric as one of the constituents which can reduce inflammation in bones and joints in animals, particularly in humans. It also deals with methods of using such herbals compositions. One aspect of the present invention is directed to an orally or topically administered composition capable of reducing inflammation in animals, preferably humans. Turmeric has been known to have anti-inflammatory properties for a long time in this country. Majority of households in India would be familiar with this property as turmeric is often used for injuries, sprain etc. It would appear that the claimed composition will have a synergy leading to higher efficacy than that of turmeric when used alone. This invention claims a composition with turmeric as one component. There are as many as 43 claims in the patent; the important ones on using turmeric are given below: 1. An orally or topically administered herbal composition for reducing inflammation in an animal, suffering from inflammation, comprising: a therapeutically effective amount of a post-supercritical carbon dioxide alcoholic extract of ginger, therapeutically effective amounts of supercritical carbon dioxide extracts of rosemary, turmeric, oregano and ginger; and therapeutically effective amounts of hydroalcoholic extracts of holy basil, turmeric, scutellariae and triamterene. 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68 TREATMENT COMPLIANCE OF RHEUMATOID ARTHRITIS PATIENTS RECEIVING INFLIXIMAB AND ETANERCEPT: THE SASKATCHEWAN EXPERIENCE WP Olszynski, KS Davison Institutions: University of Saskatchewan Funding Source: Schering Canada Inc. BACKGROUND: The recent introduction of the anti-TNF agents infliximab and etanercept constituted a therapeutic landmark in the management of rheumatoid arthritis RA ; . A major difference between these agents is mode of administration, infliximab being administered intravenously approximately every 8 weeks, while etanercept is administered subcutaneously twice weekly. At this time, no Canadian data exists comparing patient compliance to these two agents. METHODS: A retrospective analysis of the administrative claims data from the Saskatchewan Drug Plan and Extended Benefits Branch database from September 2001 to September 2003 was performed. Compliance of both patient cohorts was determined, with compliance being defined as the actual number of filled prescriptions divided by the expected number of prescriptions. RESULTS: Over two years, 355 RA patients received at least one claim for infliximab or etanercept. In order to minimize skew, only data from those patients who had been treated for a minimum of one year continuously were included in the analysis etanercept, n 91; infliximab, n 98 ; . Only 24% of etanercept patients were 100% compliant compared to 80% of infliximab patients P 0.01 ; . The percentage of patients receiving a minimum of 80% of the number of prescriptions was significantly higher P 0.01 ; for infliximab patients 91% ; than for etanercept patients 71% ; . CONCLUSION: Analysis of two years of claims data indicate that compliance is significantly higher with infliximab compared to etanercept. While it is not possible to demonstrate based upon the current data, it is reasonable to speculate that this difference in compliance may have an important KEY WORDS: Infliximab; etanercept; rheumatoid arthritis; compliance; utilization. Synthroid without prescription1. AACE Thyroid Task Force. American Association of Clinical Endocrinologists medical guidelines for clinical practice for the evaluation and treatment of hyperthroidism and hypothryroidism. Endocr Pract 2002; 8: 458-69. Yoshida H, et al. Association of serum antithyroid antibodies with lymphocytic infiltration of the thyroid gland: study of 70 autopsied cases. J Clin Endocrinol Met 1978; 46: 459. Baker JR. Autoimmune endocrine disease. JAMA 1997; 278: 1931-7. Singer PA, et al. Treatment guidelines for patients with hyperthyroidism and hypothyroidism. JAMA 1995; 273: 808-12. American College of Physicians. Clinical Guideline, Part 1: Screening for thyroid disease. Ann Intern Med 1998; 129: 141-3. American College of Physicians. Clinical Guideline, Part 2: Screening for thyroid disease: an update. Ann Intern Med1998; 129: 144-58. 7. Paul W, et al. American Thyroid Association Guidelines for Detection of Thyroid Dysfunction. Arch Intern Med 2000; 160: 1573-5. The National Academy of Clinical Biochemistry Laboratory Medicine Practice Guideline. Laboratory support for the diagnosis and monitoring of thyroid disease. Available at nacb lmpg thyroid lmpg pub m. Accessed on June 4, 2003. 9. Benvenga S, et al. Delayed intestinal absorption of levothyroxine. Thyroid 1995; 5: 249-53. Abbott Laboratories. Synthrojd package insert. In: Physicians Desk Reference. 57 th ed. Montvale NJ ; : Medical Economics Co.; 2002. 11. Mandel SJ, et al. Levothyroxine therapy in patients with thyroid disease. Ann Intern Med 1993; 119: 492-502. Mandel SJ, et al. Increased need for thyroxine during pregnancy in women with primary hypothyroidism. N Engl J Med 1990; 323: 91-6. Liel Y, et al. Evidence for a clinically important adverse effect of fiber-enriched diet on the bioavailability of levothyroxine in adult hypothyroid patients. J Clin Endocrinol Metab 1996; 80: 857-9. Singh N, et al. Effect of calcium carbonate on the absorption of levothyroxine. JAMA 2000; 283: 2822-5. Liel Y, et al. Nonspecific intestinal adsorption of levothyroxine by aluminum hydroxide. J Med 1994; 97: 363-5. Surks MI, Sievert R. Drugs and thyroid function. N Engl J Med 1995; 333: 1688-94. Stall GM, et al. Accelerated bone loss in hypothyroid patients overtreated with levothyroxine. Ann Intern Med 1990; 113: 265-9. Toft AD, Boon NA. Thyroid disease and the heart. Heart 2000; 84: 455-60. Ching GW, et al. Cardiac hypertrophy as a result of long-term thyroxine therapy and thyrotoxicosis. Heart 1996; 75: 363-8. Bernstein R, et al. Silent myocardial infarction in hypothyroidism. Thyroid 1995; 5: 443-7. Aronow WS. The heart and thyroid disease. Clin Geriatr Med 1995; 11: 219-29. Jordan RM. Myxedema coma. Pathophysiology, therapy and factors affecting prognosis. Med Clin North 1995; 79: 185-94. Gavin LA. Thyroid crisis. Med Clin North 1991; 75: 179-83. Doherty JE, Perkins WH. Digoxin metabolism in hypoand hyperthyroidism. Studies with tritiated digoxin in thyroid disease. Ann Intern Med 1966; 64: 489-507. Harjai KJ, Licata AA. Effects of amiodarone on thyroid function. Ann Intern Med 1997; 126: 63-73. Gittoes NJ, Franklyn JA. Drug-induced thyroid disorders. Drug Safety 1995; 13: 46-55. Food and Drug Administration. Electronic Orange Book. Active ingredient search result from Rx table for query on "levothyroxine." Available at: accessdata.fda.gov scripts cder ob docs tempai . Accessed on April 11, 2003. 28. Department of Public Health. Drug Control Program. Policy on drug interchangeability and midstream interchange. Available at: state.ma dph dcp dfc9734 . Accessed on April 14, 2003. 29. Food and Drug Administration. Electronic Orange Book. Preface. Available at: fda.gov cder ob docs preface ecpreface . Accessed on April 11, 2003. Side effects of synthroid 50mgPink eye how long contagious, physical growth of an infant, retinol walgreens, intractable epistaxis and larynx scope. Huntingtin protein, acute myelogenous leukemia subtypes, recalcitrant meaning and buy internet business or hemorrhoids definition. Synthroid 25Synthroid without prescription, side effects of synthroid 50mg, synthroid 25, synthroid toxicity treatment and thyroid to synthroid conversion. Did you lose weight on synthroid, synthroid mcgs, what is synthroid 50 mcg tab and generic synthroid levothyroxine or synthroid generic levothyroxine. Copyright © 2009 by Buy.atspace.name Inc.
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